Engineering

ENGINEERING DESIGN

Ingegneria_01Our Engineering support includes dedicated Facility Planning services. These services consist of the provision of layout analysis and design support as the preliminary, often strategic phase in the process of developing and/or restructuring industrial sites (whether individual departments and entire manufacturing sites).
The approach followed starts with the strategic design of a Site Master Plan that optimises the flows of materials, people and equipment in our client’s manufacturing processes in order to then specify the optimal system, technological and procedural solutions for the constraints identified.
The Site Master Plan does not concern itself solely with technical considerations, but also takes financial, research and development, purchasing, production transfer and marketing requirements into account, proposing solutions that our client company’s directors or owners can immediately recognise as offering financial and technical benefits. A distinctive feature of our services is that they also focus on analysis and design of materials handling and storage systems and equipment to support these processes, as well as an energy saving study.
CSV LIFE SCIENCE offers Conceptual Engineering, Basic and Detail Engineering services. At the same time our validation background enables CSV LIFE SCIENCE to support every project phase taking cGMP problems into account.

  • Conceptual Engineering
  • Basic Engineering
  • Detail Engineering

CSV know how and the technical background of the Chemical engineers belonging to the rich process department allows the company to face projects in both, secondary manufacturing and API fields where the process (chemical synthesis or biotech) and the relevant engineering design require special and specific technical skills together with GXP experience.

CONCEPTUAL DESIGN

CSV Life Science Engineering Team can develop a project since the very beginning, starting from Conceptual Design phase. The main activities involved in this phase are the following:

Production plant and technical plant areas definition
Lay-out and Process Flow Diagrams definition
Areas classification
Personnel/Material flow
Main process equipment and process utilities definition
Total Investment Cost Estimate (± 25 ÷ 30%)

BASIC DESIGN

Ingegneria_02The next step in design developing is the Basic Design phase. The target of this step is to consolidate what already defined during Conceptual Design and proceed developing the necessary activity to bring to a successful completion the project, such as:
Process Equipment Lay-out
Process Utilities Generation and Distribution Lay-Out
Design Criteria HVAC
P&ID HVAC
Process and technical fluids P&ID
Process P&ID
Piping Lay-Out
Duct Lay-out

Main utilities generation equipment Pre-dimensioning
Process Equipment Technical Specifications
Equipment list
Instruments list
Fluids list
Consumption list
Activities time table
Total Investment Cost Estimate (± 10 ÷ 15%)

DETAILED DESIGN AND SITE SUPERVISION

Ingegneria_03CSV Life Science can support Client in developing the Detailed Design of a Plant as a result of consolidation and completion of drawings and documents issued during the previous Basic Design phase.
CSV Life Science also assists Client in selecting the right partner for Construction phase analyzing all the offers received by Suppliers/Sub-contractors and proceeding with technical-economical tabulation.
CSV Life Science support continues through Sub-contractors follow-up phase, checking the technical offers compliance with engineering design documents.
During Construction phase CSV Life Science can support Client in Site Supervision, Construction Management and Commissioning activities.
Following Commissioning & Validation(C&Q) integration approach, tests performed on site during Construction and Commissioning phase , are documented and reported on an appropriate format (accordingly to approved Commissioning Procedures) that can ensure a strong support during IQ/OQ Protocols writing and execution.